Microtubule-associated proteins tau and amyloid P component in Alzheimer's disease

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

Bradley T. Hyman, Gary W. Van Hoesen, António R. Damásio et al. · Science · 1984 · 2.3K citations

Life Sciences, Neurobiology, Neuroscience +17

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Inge Grundke‐Iqbal, Khalid Iqbal, M Quinlan et al. · Journal of Biological Chemistry · 1986 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

K S Kosik, Catharine Joachim, D. J. Selkoe · Proceedings of the National Academy of Sciences · 1986 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +16

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

Colin L. Masters, Gerd Multhaup, G. Simms et al. · The EMBO Journal · 1985 · 1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

Claude M. Wischik, M Novák, Hans C. Thøgersen et al. · Proceedings of the National Academy of Sciences · 1988 · 944 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14