K S Kosik

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

K S Kosik, Catharine Joachim, D. J. Selkoe · Proceedings of the National Academy of Sciences · 1986 · 1.4K citations

Molecular Biology, Cytoskeleton, Microtubule-associated Protein Tau +16

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

Robert Clark, M. Hutton, M. Fuldner et al. · Nature Genetics · 1995 · 470 citations

Allelic Variant, Genetic Disorder, Genetics +7

Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.

K S Kosik, Lawrence K. Duffy, Michael M. Dowling et al. · Proceedings of the National Academy of Sciences · 1984 · 223 citations · Full text

Microtubule-associated Protein 2, Neurochemical Biomarkers, Cytoskeleton +20

Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.

Nobuyuki Nukina, K S Kosik, D. J. Selkoe · Proceedings of the National Academy of Sciences · 1987 · 198 citations · Full text

Molecular Biology, Neurochemical Biomarkers, Tau Protein +24

Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.

Steven M. Greenberg, Edward H. Koo, D. J. Selkoe et al. · Proceedings of the National Academy of Sciences · 1994 · 162 citations · Full text