Inge Grundke‐Iqbal

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

Molecular Biology, Cytoskeleton, Microtubule-associated Protein Tau +19

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Inge Grundke‐Iqbal, Khalid Iqbal, M Quinlan et al. · Journal of Biological Chemistry · 1986 · 1.8K citations · Full text

Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

Alejandra del C. Alonso, Tanweer Zaidi, Michal Novák et al. · Proceedings of the National Academy of Sciences · 2001 · 959 citations · Full text

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

A C Alonso, Inge Grundke‐Iqbal, Khalid Iqbal · Nature Medicine · 1996 · 843 citations

Alzheimer's Disease, Protein Folding, Molecular Biology +8

Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease

C. Bancher, Christof Brunner, Hans Lassmann et al. · Brain Research · 1989 · 797 citations

Alzheimer's Disease, Dementia, Neurofibrillary Tangles +10