Concepedia

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

A C Alonso, Inge Grundke‐Iqbal, Khalid Iqbal

Nature Medicine · 1996 · 854 citations · 29 references

DOI

Concepts

References

29

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

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Assay of proteins in the presence of interfering materials

André Bensadoun, David Weinstein · Analytical Biochemistry · 1976 · 3.2K citations

, , +6

Observations on the brains of demented old people

B. E. Tomlinson, G. Blessed, Martin Roth · Journal of the Neurological Sciences · 1970 · 2.1K citations

, , +12

Microtubule Assembly in the Absence of Added Nucleotides

Michael L. Shelanski, Felicia Gaskin, Charles R. Cantor · Proceedings of the National Academy of Sciences · 1973 · 2.1K citations · Full text

, , +8

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Inge Grundke‐Iqbal, Khalid Iqbal, M Quinlan et al. · Journal of Biological Chemistry · 1986 · 1.8K citations · Full text

, , +14