Concepedia

Tau Pathology

Tau Pathology is a neuropathological process characterized by abnormal post-translational modification, misfolding, and aggregation of tau protein into insoluble intracellular inclusions in neurons and/or glia that disrupt microtubule-associated functions and are closely associated with neurodegeneration.

7.6K

Publications

673.5K

Citations

32.8K

Authors

4.5K

Institutions

Publications per year

2017–2026

3.5K

Variants

Tauopathy

Parents

Children

Publications

7.6K

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

, , +17

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

, , +12

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

Heiko Braak, Irina Alafuzoff, Thomas Arzberger et al. · Acta Neuropathologica · 2006 · 3.3K citations · Full text

, , +12

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama et al. · Biochemical and Biophysical Research Communications · 2006 · 2.8K citations

, , +11

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Michel Goedert, Maria Grazia Spillantini, Ross Jakes et al. · Neuron · 1989 · 2.5K citations

, , +16

1–5 of 7.6K

Authors

32.8K

  1. JQ
    John Q. Trojanowski

    University of Pennsylvania, United States

    191 publications · 31.9K citations

    98

    h-index

  2. VM
    Virginia M.‐Y. Lee

    University of Pennsylvania, United States

    144 publications · 28.5K citations

    89

    h-index

  3. DW
    Dennis W. Dickson

    Mayo Clinic in Florida, United States

    177 publications · 25.7K citations

    79

    h-index

  4. MG
    Michel Goedert

    MRC Laboratory of Molecular Biology, United Kingdom

    94 publications · 23.2K citations

    63

    h-index

  5. KB
    Kaj Blennow

    University of Gothenburg, Sweden

    131 publications · 15.8K citations

    62

    h-index

1–5 of 32.8K

Institutions

4.5K

  1. University of Pennsylvania

    Philadelphia, United States

    116 h-index

    1.7K publications

    253.8K citations

  2. Harvard University

    Cambridge, United States

    109 h-index

    1.7K publications

    247.7K citations

  3. Mayo Clinic in Florida

    Jacksonville, United States

    96 h-index

    1.5K publications

    302.1K citations

  4. University College London

    London, United Kingdom

    95 h-index

    1.1K publications

    120.1K citations

  5. University of California, San Francisco

    San Francisco, United States

    94 h-index

    1.1K publications

    174K citations

  6. Massachusetts General Hospital

    Boston, United States

    90 h-index

    1.5K publications

    199.7K citations

  7. Inserm

    Paris, France

    81 h-index

    1.3K publications

    114.6K citations

  8. Brigham and Women's Hospital

    Boston, United States

    77 h-index

    548 publications

    83.2K citations

1–8 of 4.5K

Venues

  1. Journal of Neuroscience

    179 publications · 31.9K citations

    104

    h-index

  2. Journal of Biological Chemistry

    JBC · 171 publications · 27.7K citations

    96

    h-index

  3. Brain

    169 publications · 28.2K citations

    94

    h-index

  4. Acta Neuropathologica

    264 publications · 31.5K citations

    92

    h-index

  5. Neurobiology of Aging

    222 publications · 17.4K citations

    73

    h-index

1–5