Concepedia

Tau Acetylation

Tau Acetylation is a post-translational modification of the tau protein characterized by the addition of an acetyl group to specific lysine residues, which distinguishes it from other tau modifications by altering tau's conformation, stability, and propensity to aggregate in the context of neurodegenerative tauopathies.

91

Publications

8.7K

Citations

655

Authors

236

Institutions

Publications per year

2017–2026

57

Parents

Publications

91

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

Sang-Won Min, Seo-Hyun Cho, Yungui Zhou et al. · Neuron · 2010 · 925 citations · Full text

, , +9

The acetylation of tau inhibits its function and promotes pathological tau aggregation

Todd J. Cohen, Jing Guo, David Hurtado et al. · Nature Communications · 2011 · 717 citations · Full text

, , +12

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Sang‐Won Min, Xu Chen, Tara E. Tracy et al. · Nature Medicine · 2015 · 503 citations · Full text

, , +16

The Microtubule-associated Protein Tau Is Extensively Modified with O-linked N-acetylglucosamine

C. Shane Arnold, GailV.W. Johnson, Robert N. Cole et al. · Journal of Biological Chemistry · 1996 · 342 citations · Full text

, , +10

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

Casey Cook, Yari Carlomagno, Tania F. Gendron et al. · Human Molecular Genetics · 2013 · 297 citations · Full text

, , +17

1–5 of 91

Authors

655

  1. LG
    Li Gan

    Gladstone Institutes, United States

    10 publications · 2.6K citations

    10

    h-index

  2. TJ
    Todd J. Cohen

    University of North Carolina at Chapel Hill, United States

    10 publications · 1.6K citations

    10

    h-index

  3. VM
    Virginia M.‐Y. Lee

    University of Pennsylvania, United States

    6 publications · 1.4K citations

    6

    h-index

  4. PS
    Peter Sohn

    Gladstone Institutes, United States

    6 publications · 1.4K citations

    6

    h-index

  5. YZ
    Yungui Zhou

    University of California, San Francisco, United States

    5 publications · 1.9K citations

    5

    h-index

1–5 of 655

Institutions

236

  1. University of California, San Francisco

    San Francisco, United States

    10 h-index

    62 publications

    16.9K citations

  2. Gladstone Institutes

    San Francisco, United States

    9 h-index

    53 publications

    18.1K citations

  3. University of Pennsylvania

    Philadelphia, United States

    8 h-index

    39 publications

    8.5K citations

  4. Nantong University

    Nantong, China

    8 h-index

    35 publications

    863 citations

  5. Cornell University

    Ithaca, United States

    6 h-index

    24 publications

    1.8K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    32 publications

    2.3K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    23 publications

    1.2K citations

  8. Huazhong University of Science and Technology

    Wuhan, China

    6 h-index

    57 publications

    2.3K citations

1–8 of 236

Venues

  1. Molecular Neurodegeneration

    MN · 6 publications · 480 citations

    6

    h-index

  2. Nature Communications

    6 publications · 1.4K citations

    6

    h-index

  3. Scientific Reports

    5 publications · 328 citations

    5

    h-index

  4. Journal of Biological Chemistry

    JBC · 5 publications · 578 citations

    5

    h-index

  5. Journal of Alzheimer s Disease

    JAD · 4 publications · 242 citations

    4

    h-index

1–5