Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: A preliminary study using a multiplexing approach

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

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Pharmacy, Pharmacology, Toxicology +16

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

Walter M.A. Westerink, W.G.E.J. Schoonen · Toxicology in Vitro · 2007 · 525 citations

Medicine, Biochemistry, Pharmacology +16

A practical note on the use of cytotoxicity assays

Jörg Weyermann, Dirk Lochmann, Andreas Zimmer · International Journal of Pharmaceutics · 2004 · 516 citations

Pharmacy, Cell Biology, Toxicology +9

Use of Multiple Assay Endpoints to Investigate the Effects of Incubation Time, Dose of Toxin, and Plating Density in Cell-Based Cytotoxicity Assays

Terry Riss, Richard A Moravec · Assay and Drug Development Technologies · 2004 · 365 citations

Pharmacy, Pharmacology, Toxicology +16

Drug metabolism by the human hepatoma cell, Hep G2

Shigeru Sassa, Osamu Sugita, Richard A. Galbraith et al. · Biochemical and Biophysical Research Communications · 1987 · 191 citations

Medicine, Biochemistry, Pharmacology +15