Dolores Diaz

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 609 citations

Pharmacy, Pharmacology, Toxicology +16

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 320 citations

Medicine, Oncology, Pharmacology +17

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease

Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry et al. · Science Translational Medicine · 2022 · 252 citations

Life Sciences, Neuroscience, Pharmacology +17

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 229 citations · Full text

Life Sciences, Genetics, Neuroscience +12

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

Julie C. Ullman, Annie Arguello, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 205 citations

Pharmacy, Neuroscience, Pharmaceutics +17