Concepedia
Statistics
Publications
9
Citations
723
H-Index
Active since
2013
Affiliations
Denali Therapeutics (United States)(Current)
University of California, San Francisco
Annie Arguello is an author at Denali Therapeutics (United States) specializing in medicine, neuroscience, and neurology.
Top concepts
MedicineNeurologyNeuroscienceCell BiologyNeuroimmunologyNeuroinflammationImmunologyPharmacologyNeuropathologySocial Sciences
Publications per year
2013–2024
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry et al. · Science Translational Medicine · 2022 · 230 citations
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
Julie C. Ullman, Annie Arguello, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 194 citations
Molecular Neuroscience, Blood–brain Barrier, Medicine +15
Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme
Annie Arguello, Cathal Mahon, Meredith Calvert et al. · The Journal of Experimental Medicine · 2021 · 80 citations · Full text
Immunology, Synaptic Signaling, Social Sciences +22
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
Jing Guo, Dylan Braun, Gabriel A. Fitzgerald et al. · Cell · 2024 · 63 citations · Full text
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10
Xiang Wang, Elvira Negrou, Michael T. Maloney et al. · Scientific Reports · 2021 · 58 citations · Full text
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