Meredith Calvert

Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys

Mihalis S. Kariolis, Robert C. Wells, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 355 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 229 citations · Full text

Life Sciences, Genetics, Neuroscience +12

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 222 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation

Keh‐Weei Tzung, Rie Goto, Jolly M. Saju et al. · Stem Cell Reports · 2014 · 198 citations · Full text

Life Sciences, Biology, Developmental Biology +17

ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets

Paul W. Wright, Laura Bolling, Meredith Calvert et al. · Developmental Biology · 2003 · 155 citations

Life Sciences, Biochemistry, Molecular Biology +9