Concepedia

Bettina van Lengerich

BV

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Publications

17

Citations

2.5K

H-Index

15

Active since

2004

Affiliations

Denali Therapeutics (United States)(Current)

Stanford University

University of California, San Francisco

German Center for Neurodegenerative Diseases

Munich Cluster for Systems Neurology

Bettina van Lengerich is an author at Denali Therapeutics (United States) specializing in life sciences, biochemistry, and molecular biology.

Publications per year

2004–2026

17

Publications

17

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 748 citations · Full text

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Effects of linker sequences on vesicle fusion mediated by lipid-anchored DNA oligonucleotides

Yee-Hung M. Chan, Bettina van Lengerich, Steven G. Boxer · Proceedings of the National Academy of Sciences · 2009 · 286 citations · Full text

, , +17

Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia

Benjamin J. Andreone, Laralynne Przybyla, Ceyda Llapashtica et al. · Nature Neuroscience · 2020 · 247 citations

, , +17

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 229 citations · Full text

, , +12

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 222 citations · Full text

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