Dan Xia

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 697 citations · Full text

Inflammation, Immunology, Chronic Inflammation +7

Enhancing protective microglial activities with a dual function <scp>TREM</scp> 2 antibody to the stalk region

Kai Schlepckow, Kathryn M. Monroe, Gernot Kleinberger et al. · EMBO Molecular Medicine · 2020 · 335 citations · Full text

Presenilin-1 Knockin Mice Reveal Loss-of-Function Mechanism for Familial Alzheimer’s Disease

Dan Xia, Hirotaka Watanabe, Bei Wu et al. · Neuron · 2015 · 228 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Alzheimer's Disease +11

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 213 citations · Full text

A highly flexible and multifunctional strain sensor based on a network-structured MXene/polyurethane mat with ultra-high sensitivity and a broad sensing range

Kai Yang, Fuxing Yin, Dan Xia et al. · Nanoscale · 2019 · 195 citations