Karin Lin

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

Saul Villeda, Kristopher E. Plambeck, Jinte Middeldorp et al. · Nature Medicine · 2014 · 1.1K citations · Full text

Young Blood, Synaptic Plasticity, Alzheimer's Disease +8

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 697 citations · Full text

Inflammation, Immunology, Chronic Inflammation +7

β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis

Lucas K. Smith, Yingbo He, Jeong‐Soo Park et al. · Nature Medicine · 2015 · 492 citations · Full text

Developmental Biology, Alzheimer's Disease, Aging +8

Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia

Benjamin J. Andreone, Laralynne Przybyla, Ceyda Llapashtica et al. · Nature Neuroscience · 2020 · 235 citations

Inflammation, Trem2 Function, Neurodegenerative Diseases +14

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

Alexandra Litvinchuk, Jung H. Suh, Jing Guo et al. · Neuron · 2023 · 115 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +5