Ceyda Llapashtica

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 697 citations · Full text

Inflammation, Immunology, Chronic Inflammation +7

Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia

Benjamin J. Andreone, Laralynne Przybyla, Ceyda Llapashtica et al. · Nature Neuroscience · 2020 · 235 citations

Inflammation, Trem2 Function, Neurodegenerative Diseases +14

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 210 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Lysosomal Storage Disorder +11

Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder

Job O. de Jong, Ceyda Llapashtica, Matthieu Genestine et al. · Nature Communications · 2021 · 120 citations · Full text

Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10

Xiang Wang, Elvira Negrou, Michael T. Maloney et al. · Scientific Reports · 2021 · 58 citations · Full text