Ted Lau

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

Maia Vinogradova, Victor Gehling, Amy Gustafson et al. · Nature Chemical Biology · 2016 · 343 citations · Full text

Drug-tolerant Cancer Cells, Medicine, Anti-cancer Agent +7

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 317 citations

Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling

Marinella Callow, Hoanh Tran, Lilian Phu et al. · PLoS ONE · 2011 · 222 citations · Full text

Molecular Regulation, Axin Scaffolding, Rnf146 Protein Levels +20

Inhibition of Wnt signaling by Dishevelled PDZ peptides

Yingnan Zhang, B.A. Appleton, Christian Wiesmann et al. · Nature Chemical Biology · 2009 · 160 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +4

Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index &lt; 1

Yu Zhong, Paula Katavolos, Tien‐Trung Nguyen et al. · Toxicologic Pathology · 2015 · 98 citations · Full text

Gastrointestinal Pharmacology, Gastroenterology, Pathology +16