Helga H.J. Gerets

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

Helga H.J. Gerets, Karen Tilmant, Brigitte Gerin et al. · Cell Biology and Toxicology · 2012 · 664 citations · Full text

Pathology, Heparg Cells, Oxidative Stress +23

The Use of Real-Time Cell Analyzer Technology in Drug Discovery: Defining Optimal Cell Culture Conditions and Assay Reproducibility with Different Adherent Cellular Models

Franck A. Atienzar, Karen Tilmant, Helga H.J. Gerets et al. · SLAS DISCOVERY · 2011 · 101 citations · Full text

Engineering, Cell Culture, Biomedical Engineering +22

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

Rowena Sison‐Young, Volker M. Lauschke, Esther Johann et al. · Archives of Toxicology · 2016 · 100 citations · Full text

Cell Health, Immunology, Pathology +25

Genetic toxicology in silico protocol

Catrin Hasselgren, Ernst Ahlberg, Yumi Akahori et al. · Regulatory Toxicology and Pharmacology · 2019 · 78 citations · Full text

Engineering, Genetics, Toxicology Testing +17

Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: A preliminary study using a multiplexing approach

Helga H.J. Gerets, Étienne Hanon, Miranda Cornet et al. · Toxicology in Vitro · 2008 · 70 citations

Medicinal Chemistry, New Chemical Entities, Pharmaceutical Research +14