cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

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Nomenclature Committee, Medicine, Apoptosis +8

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

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Apoptosis, Cell Death, Pharmacotherapy +16

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Inflammation, Phosphorylation-driven Assembly, Viral Replication +9

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

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Inflammation, Cytokine, Signal Transduction +11

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

Signal Transduction, Signaling Pathway, Cell Regulation +6