Domagoj Vucic

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Sanjeev Mariathasan, Kim Newton, Denise M. Monack et al. · Nature · 2004 · 1.8K citations

Inflammation, Anti-inflammatory, Signal Transduction +11

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Eugene Varfolomeev, John W. Blankenship, Sarah M. Wayson et al. · Cell · 2007 · 1.2K citations · Full text

Inflammation, Cytokine, Induce Autoubiquitination +12

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

Kim Newton, Debra L. Dugger, Katherine E. Wickliffe et al. · Science · 2014 · 668 citations · Full text

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

Eugene Varfolomeev, Tatiana Goncharov, Anna Fedorova et al. · Journal of Biological Chemistry · 2008 · 532 citations · Full text

Apoptosis, Immunology, Immune Regulation +21

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

Kim Newton, Debra L. Dugger, Allie Maltzman et al. · Cell Death and Differentiation · 2016 · 433 citations · Full text