Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce, +7

Nature Chemical Biology

ApoptosisCell DeathPharmacotherapyGliomaOxidative Stress +14

A Selective Inhibitor of eIF2α Dephosphorylation Protects Cells from ER Stress

Michael Boyce, Kevin F. Bryant, Céline Jousse, +8

Science

Most Protein PhosphatasesEr StressSubunit AlphaCellular PhysiologyOxidative Stress +17

Metabolic cross-talk allows labeling of O-linked β- <i>N</i> -acetylglucosamine-modified proteins via the <i>N</i> -acetylgalactosamine salvage pathway

Michael Boyce, Isaac S. Carrico, Anjali S. Ganguli, +5

Proceedings of the National Academy of Sciences

GlycobiologyMolecular BiologyMetabolic Cross-talkChemical BiologyProtein Synthesis +15

Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis

Miriam Cnop, Laurence Ladrière, Paul Hekerman, +7

Journal of Biological Chemistry

Bringing chemistry to life

Michael Boyce, Carolyn R. Bertozzi

Nature Methods

Environmental ChemistryEngineeringGreen ChemistryPhilosophy Of ChemistryChemistry +2

The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA

Rodolfo Zentella, Ning Sui, Benjamin Barnhill, +8

Nature Chemical Biology

BiologyPlant Molecular BiologyBiosynthesisEngineeringGenetics +3

Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners

Seok‐Ho Yu, Michael Boyce, Amberlyn M. Wands, +3

Proceedings of the National Academy of Sciences

<i>O</i>-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in<i>Arabidopsis</i>

Rodolfo Zentella, Jianhong Hu, Wen‐Ping Hsieh, +13

Genes & Development

Glycosylation of <scp>KEAP</scp> 1 links nutrient sensing to redox stress signaling

Po‐Han Chen, Timothy J. Smith, Jianli Wu, +11

The EMBO Journal

A genome-wide RNAi screen reveals multiple regulators of caspase activation

Caroline H. Yi, Dodzie K. Sogah, Michael Boyce, +3

The Journal of Cell Biology

EngineeringGeneticsApoptosisMolecular BiologyCell Death +14