Laurence Ladrière

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Daniel A. Cunha, Paul Hekerman, Laurence Ladrière et al. · Journal of Cell Science · 2008 · 584 citations · Full text

Lipid Peroxidation, Apoptosis, Cell Death +23

Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress

Ilham Kharroubi, Laurence Ladrière, Alessandra K. Cardozo et al. · Endocrinology · 2004 · 576 citations

Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis

Miriam Cnop, Laurence Ladrière, Paul Hekerman et al. · Journal of Biological Chemistry · 2006 · 284 citations · Full text

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

Miriam Cnop, Baroj Abdulkarim, Guy Bottu et al. · Diabetes · 2013 · 258 citations · Full text

Genetics, Cell Death, Transcriptomics Technology +21

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

Mariana Igoillo‐Esteve, Lorella Marselli, Daniel A. Cunha et al. · Diabetologia · 2010 · 230 citations · Full text

Inflammation, Mimics Ccl2 Expression, Signal Transduction +12