Mariana Igoillo‐Esteve

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Décio L. Eizirik, Michael Sammeth, Thomas Bouckenooghe et al. · PLoS Genetics · 2012 · 472 citations · Full text

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Michael Volkmar, Sarah Dedeurwaerder, Daniel A. Cunha et al. · The EMBO Journal · 2012 · 426 citations · Full text

Chromatin, Pancreatic Islets, Epigenetic Change +11

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

Miriam Cnop, Baroj Abdulkarim, Guy Bottu et al. · Diabetes · 2013 · 258 citations · Full text

Genetics, Cell Death, Transcriptomics Technology +21

The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

Miriam Cnop, Stephen J. Hughes, Mariana Igoillo‐Esteve et al. · Diabetologia · 2009 · 241 citations · Full text

Longevity, Insulin Management, Physiology +11

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

Mariana Igoillo‐Esteve, Lorella Marselli, Daniel A. Cunha et al. · Diabetologia · 2010 · 230 citations · Full text

Inflammation, Mimics Ccl2 Expression, Signal Transduction +12