TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

Rachel Deplus, Benjamin Delatte, Marie K. Schwinn, +15

The EMBO Journal

ChromatinSignal TransductionBiochemistryNatural SciencesEpigenetic Change +6

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Michael Volkmar, Sarah Dedeurwaerder, Daniel A. Cunha, +14

The EMBO Journal

ChromatinPancreatic IsletsEpigenetic ChangeGeneticsDna Methylation +9

DNA methylation profiling reveals a predominant immune component in breast cancers

Sarah Dedeurwaerder, Christine Desmedt, Emilie Calonne, +23

EMBO Molecular Medicine

Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

Isabel Poschke, Marta Faryna, Frank Bergmann, +18

OncoImmunology

Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

Daniel Baumann, Tanja Hägele, Julian Mochayedi, +12

Nature Communications

Minichromosome Maintenance Protein 3 Elicits a Cancer-Restricted Immune Response in Patients with Brain Malignancies and Is a Strong Independent Predictor of Survival in Patients with Anaplastic Astrocytoma

Ariane Söling, Mirko Sackewitz, Michael Volkmar, +4

Clinical Cancer Research

Transcriptome-based identification of tumor-reactive and bystander CD8 ⁺ T cell receptor clonotypes in human pancreatic cancer

Zibo Meng, Aaron Rodriguez Ehrenfried, Chin Leng Tan, +16

Science Translational Medicine

Trans-splicing of the mod(mdg4) Complex Locus Is Conserved Between the Distantly Related Species Drosophila melanogaster and D. virilis

Manuela Gabler, Michael Volkmar, Susan Weinlich, +8

Genetics

GeneticsRna SplicingGenomic MechanismMolecular BiologyMolecular Genetics +19

The histone demethylase Kdm3a is essential to progression through differentiation

Mariëlle Herzog, Eléonore Josseaux, Sarah Dedeurwaerder, +3

Nucleic Acids Research

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display

Stina L. Wickström, Tanja Lövgren, Michael Volkmar, +14

Frontiers in Immunology