Daniel A. Cunha

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Daniel A. Cunha, Paul Hekerman, Laurence Ladrière et al. · Journal of Cell Science · 2008 · 584 citations · Full text

Lipid Peroxidation, Apoptosis, Cell Death +23

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Michael Volkmar, Sarah Dedeurwaerder, Daniel A. Cunha et al. · The EMBO Journal · 2012 · 426 citations · Full text

Chromatin, Pancreatic Islets, Epigenetic Change +11

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

Miriam Cnop, Baroj Abdulkarim, Guy Bottu et al. · Diabetes · 2013 · 258 citations · Full text

Genetics, Cell Death, Transcriptomics Technology +21

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

Mariana Igoillo‐Esteve, Lorella Marselli, Daniel A. Cunha et al. · Diabetologia · 2010 · 230 citations · Full text

Inflammation, Mimics Ccl2 Expression, Signal Transduction +12

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

Daniel A. Cunha, Laurence Ladrière, Fernanda Ortis et al. · Diabetes · 2009 · 217 citations · Full text