Décio L. Eizirik

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Daniel A. Cunha, Paul Hekerman, Laurence Ladrière et al. · Journal of Cell Science · 2008 · 584 citations · Full text

Lipid Peroxidation, Apoptosis, Cell Death +23

Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress

Ilham Kharroubi, Laurence Ladrière, Alessandra K. Cardozo et al. · Endocrinology · 2004 · 576 citations

Inverse Relationship Between Cytotoxicity of Free Fatty Acids in Pancreatic Islet Cells and Cellular Triglyceride Accumulation

Miriam Cnop, Jean Claude Hannaert, Anne Hoorens et al. · Diabetes · 2001 · 548 citations · Full text

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Alessandra K. Cardozo, Fernanda Ortis, Joachim Størling et al. · Diabetes · 2005 · 513 citations · Full text

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Décio L. Eizirik, Michael Sammeth, Thomas Bouckenooghe et al. · PLoS Genetics · 2012 · 472 citations · Full text