Concepedia

Necrosis

Necrosis is a form of pathological cell death in living tissue that is characterized by irreversible injury leading to loss of plasma membrane integrity, enzymatic degradation and swelling of cellular components, and an associated inflammatory response, typically resulting from exogenous noxious stimuli such as ischemia, toxins, or infection.

14.3K

Publications

878.7K

Citations

57.8K

Authors

6.9K

Institutions

Publications per year

2017–2026

2.1K

Parents

Children

Publications

14.3K

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.2K citations

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Apoptosis, oncosis, and necrosis. An overview of cell death.

Guido Majno, I Joris · PubMed · 1995 · 3.3K citations

, , +12

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

Guido Kroemer, Lorenzo Galluzzi, Peter Vandenabeele et al. · Cell Death and Differentiation · 2008 · 3.3K citations · Full text

, , +11

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Liming Sun, Huayi Wang, Zhigao Wang et al. · Cell · 2012 · 2.7K citations · Full text

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1–5 of 14.3K

Authors

57.8K

  1. PV
    Peter Vandenabeele

    Ghent University, Belgium

    56 publications · 14.1K citations

    43

    h-index

  2. JM
    James M. Murphy

    Walter and Eliza Hall Institute of Medical Research, Australia

    41 publications · 5.7K citations

    31

    h-index

  3. JY
    Junying Yuan

    Harvard University, United States

    33 publications · 10.8K citations

    28

    h-index

  4. JH
    Jiahuai Han

    Scripps Research Institute, United States

    26 publications · 7.7K citations

    25

    h-index

  5. AL
    Andreas Linkermann

    University Hospital Carl Gustav Carus, Germany

    25 publications · 6.3K citations

    23

    h-index

1–5 of 57.8K

Institutions

6.9K

  1. Harvard University

    Cambridge, United States

    86 h-index

    762 publications

    111.5K citations

  2. Massachusetts General Hospital

    Boston, United States

    58 h-index

    448 publications

    45.7K citations

  3. Johns Hopkins University

    Baltimore, United States

    55 h-index

    335 publications

    46.3K citations

  4. Inserm

    Paris, France

    55 h-index

    709 publications

    70.4K citations

  5. National Institutes of Health

    Bethesda, United States

    51 h-index

    340 publications

    51.4K citations

  6. Ghent University

    Ghent, Belgium

    47 h-index

    314 publications

    54.7K citations

  7. University of Washington

    Seattle, United States

    46 h-index

    215 publications

    26.5K citations

  8. University College London

    London, United Kingdom

    46 h-index

    334 publications

    29.3K citations

1–8 of 6.9K

Venues

  1. PubMed

    Repository · 1.6K publications · 70.9K citations

    110

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 86 publications · 26.3K citations

    70

    h-index

  3. Cell Death and Differentiation

    CDD · 91 publications · 15.2K citations

    60

    h-index

  4. Cell Death and Disease

    124 publications · 10.2K citations

    60

    h-index

  5. Journal of Biological Chemistry

    JBC · 86 publications · 10.5K citations

    54

    h-index

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