Nele Vanlangenakker

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

Tom Vanden Berghe, Nele Vanlangenakker, Eef Parthoens et al. · Cell Death and Differentiation · 2009 · 620 citations · Full text

Medicine, Pathogenesis, Apoptosis +8

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Nele Vanlangenakker, Tom Vanden Berghe, Pieter Bogaert et al. · Cell Death and Differentiation · 2010 · 334 citations · Full text

Inflammation, Cytokine, Reductive Stress +10

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

Nele Vanlangenakker, Mathieu J.M. Bertrand, Pieter Bogaert et al. · Cell Death and Disease · 2011 · 227 citations · Full text

Apoptosis, Immunology, Immune Regulation +22

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten Remijsen, Vera Goossens, Sasker Grootjans et al. · Cell Death and Disease · 2014 · 192 citations · Full text

Mitophagy, Apoptosis, Immunology +20

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon J. Tavernier, Fabiola Osorio, Lana Vandersarren et al. · Nature Cell Biology · 2017 · 101 citations · Full text

Signal Transduction, Cell Regulation, Molecular Regulation +9