Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

Dominique Vercammen, Rudi Beyaert, Geertrui Denecker, +6

The Journal of Experimental Medicine

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.

Vera Goossens, Johan Grooten, Kurt J. De Vos, +1

Proceedings of the National Academy of Sciences

Tnf StimulationLipid PeroxidationImmunologyPathologyCell Death +18

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

Linde Duprez, Nozomi Takahashi, Filip Van Hauwermeiren, +7

Immunity

InflammationAutoimmune DiseaseImmunologyCell DeathChronic Inflammation +5

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Nozomi Takahashi, Linde Duprez, Sasker Grootjans, +13

Cell Death and Disease

Critical IssuesApoptosisImmune RegulationImmunologyCell Death +25

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

Nozomi Takahashi, Lars Vereecke, Mathieu J.M. Bertrand, +15

Nature

Intestinal HomeostasisReceptor Tyrosine KinaseApoptosisGastroenterologyCell Death +6

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten Remijsen, Vera Goossens, Sasker Grootjans, +11

Cell Death and Disease

MitophagyApoptosisImmunologyCell DeathPathology +18

Isolation and Characterization of Broadly Neutralizing Human Monoclonal Antibodies to the E1 Glycoprotein of Hepatitis C Virus

Jean‐Christophe Meunier, Rodney S. Russell, Vera Goossens, +8

Journal of Virology

E1 GlycoproteinHepatitis C VirusImmunologyHcv Glycoprotein E1Viral Structural Protein +17

The 55-kDa Tumor Necrosis Factor Receptor Induces Clustering of Mitochondria through Its Membrane-proximal Region

Kurt J. De Vos, Vera Goossens, Elke Boone, +6

Journal of Biological Chemistry

Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death

Sandy Adjemian, Teodora Oltean, Sofie Martens, +11

Cell Death and Disease

Tumor Necrosis Factor Induces Hyperphosphorylation of Kinesin Light Chain and Inhibits Kinesin-Mediated Transport of Mitochondria

Kurt J. De Vos, Fedor F. Severin, Franky Van Herreweghe, +4

The Journal of Cell Biology

MitophagyPathologyMolecular BiologyCytoskeletonCellular Physiology +16