Sasker Grootjans

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Nozomi Takahashi, Linde Duprez, Sasker Grootjans et al. · Cell Death and Disease · 2012 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

Yves Dondelinger, Miguel Aguileta, V Goossens et al. · Cell Death and Differentiation · 2013 · 310 citations · Full text

Life Sciences, Cell Biology, Pathobiology +13

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Özge Canli, Yasemin B. Alankuş, Sasker Grootjans et al. · Blood · 2015 · 245 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten Remijsen, Vera Goossens, Sasker Grootjans et al. · Cell Death and Disease · 2014 · 194 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

A real-time fluorometric method for the simultaneous detection of cell death type and rate

Sasker Grootjans, Behrouz Hassannia, Iris Delrue et al. · Nature Protocols · 2016 · 65 citations

Life Sciences, Biomedical Engineering, Cell Biology +13