Sasker Grootjans

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Nozomi Takahashi, Linde Duprez, Sasker Grootjans et al. · Cell Death and Disease · 2012 · 438 citations · Full text

Critical Issues, Apoptosis, Immune Regulation +27

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

Yves Dondelinger, Miguel Aguileta, V Goossens et al. · Cell Death and Differentiation · 2013 · 302 citations · Full text

Signal Transduction, Signaling Pathway, Apoptosis +8

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Özge Canli, Yasemin B. Alankuş, Sasker Grootjans et al. · Blood · 2015 · 238 citations · Full text

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten Remijsen, Vera Goossens, Sasker Grootjans et al. · Cell Death and Disease · 2014 · 192 citations · Full text

Mitophagy, Apoptosis, Immunology +20

A real-time fluorometric method for the simultaneous detection of cell death type and rate

Sasker Grootjans, Behrouz Hassannia, Iris Delrue et al. · Nature Protocols · 2016 · 64 citations

Simultaneous Detection, Real-time Fluorometric Method, Bioimage Analysis +6