Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.2K citations · Full text

Engineering, Genetics, Molecular Biology +16

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

Haoyi Wang, Hui Yang, Chikdu Shivalila et al. · Cell · 2013 · 3.5K citations · Full text

Off-target Effect, Engineering, Genome Surgery +12

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Wenyan Jiang, David Bikard, David Cox et al. · Nature Biotechnology · 2013 · 2.5K citations · Full text

Crispr-cas Systems, Genetic Engineering, Molecular Biology +5

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

Hui Yang, Haoyi Wang, Chikdu Shivalila et al. · Cell · 2013 · 1.6K citations · Full text

Knockout Mouse, Engineering, Genome Surgery +13

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

Lee Kamentsky, Thouis R. Jones, Adam Fraser et al. · Bioinformatics · 2011 · 1K citations · Full text