Hidde L. Ploegh

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Luke A. Gilbert, Max A. Horlbeck, Britt Adamson et al. · Cell · 2014 · 2.8K citations · Full text

Transcriptional Regulation, Genetics, Genetic Engineering +7

CX ₃ CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

Jan Hendrik Niess, Stephan Brand, Xiubin Gu et al. · Science · 2005 · 1.6K citations

Specialized Dcs, Innate Immune System, Immunology +18

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Takeshi Maruyama, Stephanie K. Dougan, Matthias C. Truttmann et al. · Nature Biotechnology · 2015 · 1.1K citations · Full text

Nonhomologous End Joining, Genetics, Precise Genome +7

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

Emmanuel J. H. J. Wiertz, Domenico Tortorella, Matthew Bogyo et al. · Nature · 1996 · 1.1K citations

Sec6l-mediated Transfer, Protein Secretion, Biochemistry +10

The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

Emmanuel J. H. J. Wiertz, Thomas R. Jones, Lei Sun et al. · Cell · 1996 · 1.1K citations · Full text

Virus Structure, Viral Replication, Pathogenesis +7