Emmanuel J. H. J. Wiertz

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

Emmanuel J. H. J. Wiertz, Domenico Tortorella, Matthew Bogyo et al. · Nature · 1996 · 1.1K citations

Sec6l-mediated Transfer, Protein Secretion, Biochemistry +10

The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

Emmanuel J. H. J. Wiertz, Thomas R. Jones, Lei Sun et al. · Cell · 1996 · 1.1K citations · Full text

Virus Structure, Viral Replication, Pathogenesis +7

The ER-Luminal Domain of the HCMV Glycoprotein US6 Inhibits Peptide Translocation by TAP

Kwangseog Ahn, Albrecht Gruhler, Begoña Galocha et al. · Immunity · 1997 · 476 citations

Signal Transduction, Er-luminal Domain, Immunology +7

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.

Thomas R. Jones, Emmanuel J. H. J. Wiertz, Lei Sun et al. · Proceedings of the National Academy of Sciences · 1996 · 410 citations

Human Cytomegalovirus Us3, Viral Replication, Mhc Class +16

Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum

Marjolein Kikkert, Ram Doolman, Min Dai et al. · Journal of Biological Chemistry · 2004 · 390 citations · Full text