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Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

Prasanna Venkatraman, Ronald Wetzel, Motomasa Tanaka, Nobuyuki Nukina, Alfred L. Goldberg

Molecular Cell · 2004 · 416 citations · 34 references

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34

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

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Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

Neil Bence, Roopal M. Sampat, Ron R. Kopito · Science · 2001 · 2.2K citations

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

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A gated channel into the proteasome core particle.

M. Groll, Michael H. Glickman, Daniel Finley et al. · Nature Structural Biology · 2000 · 808 citations

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