Ronald Wetzel

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

Songming Chen, Frank A. Ferrone, Ronald Wetzel · Proceedings of the National Academy of Sciences · 2002 · 524 citations · Full text

Protein Assembly, Genetics, Molecular Biology +18

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

Ashwani Kumar Thakur, Murali Jayaraman, Rakesh Kumar Mishra et al. · Nature Structural & Molecular Biology · 2009 · 448 citations · Full text

Complex Aggregation Mechanism, Signal Transduction, Biochemistry +10

Seeding Specificity in Amyloid Growth Induced by Heterologous Fibrils

Brian O’Nuallain, Angela D. Williams, Per Westermark et al. · Journal of Biological Chemistry · 2004 · 417 citations · Full text

Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

Prasanna Venkatraman, Ronald Wetzel, Motomasa Tanaka et al. · Molecular Cell · 2004 · 415 citations · Full text

Protein Chemistry, Eukaryotic Proteasomes, Protein Function +13

Mapping Aβ Amyloid Fibril Secondary Structure Using Scanning Proline Mutagenesis

Angela D. Williams, Erik Portelius, Indu Kheterpal et al. · Journal of Molecular Biology · 2003 · 379 citations

Biochemistry, Protein Assembly, Protein Folding +6