Motomasa Tanaka

Conformational variations in an infectious protein determine prion strain differences

Motomasa Tanaka, Peter Chien, Nariman Naber et al. · Nature · 2004 · 773 citations

Structural Bioinformatics, Protein Folding, Medicine +9

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

Motomasa Tanaka, Yoko Machida, Sanyong Niu et al. · Nature Medicine · 2004 · 773 citations

Biochemistry, Natural Sciences, Molecular Biology +8

The physical basis of how prion conformations determine strain phenotypes

Motomasa Tanaka, Sean R. Collins, Brandon H. Toyama et al. · Nature · 2006 · 594 citations

Biophysical Modeling, Pattern Formation, Protein Folding +10

Aβ Secretion and Plaque Formation Depend on Autophagy

Per Nilsson, Krishnapriya Loganathan, Misaki Sekiguchi et al. · Cell Reports · 2013 · 454 citations · Full text

Autophagy Deficiency, Cell Death, Neurochemical Biomarkers +23

Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

Prasanna Venkatraman, Ronald Wetzel, Motomasa Tanaka et al. · Molecular Cell · 2004 · 415 citations · Full text

Protein Chemistry, Eukaryotic Proteasomes, Protein Function +13