Conformational variations in an infectious protein determine prion strain differences

Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity

Glenn C. Telling, Piero Parchi, Stephen J. DeArmond et al. · Science · 1996 · 872 citations

Veterinary Medicine, Biochemistry, Molecular Biology +17

Self-Seeded Fibers Formed by Sup35, the Protein Determinant of [PSI+], a Heritable Prion-like Factor of S. cerevisiae

John R. Glover, Anthony S. Kowal, Eric C. Schirmer et al. · Cell · 1997 · 599 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Motion of Spin-Labeled Side Chains in T4 Lysozyme. Correlation with Protein Structure and Dynamics

Hassane S. Mchaourab, Michael A. Lietzow, Kálmán Hideg et al. · Biochemistry · 1996 · 559 citations

Natural Sciences, Biochemistry, Biophysics +17

Genesis and Variability of [<i>PSI</i>] Prion Factors in <i>Saccharomyces cerevisiae</i>

Irina L. Derkatch, Yury O. Chernoff, Vitaly V. Kushnirov et al. · Genetics · 1996 · 533 citations

Life Sciences, Biology, Genetics +13

Non-genetic propagation of strain-specific properties of scrapie prion protein

Richard A. Bessen, David A. Kocisko, Gregory J. Raymond et al. · Nature · 1995 · 523 citations

Veterinary Medicine, Genetics, Molecular Biology +14