Ashwani Kumar Thakur

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

Ashwani Kumar Thakur, Murali Jayaraman, Rakesh Kumar Mishra et al. · Nature Structural & Molecular Biology · 2009 · 448 citations · Full text

Complex Aggregation Mechanism, Signal Transduction, Biochemistry +10

Oligoproline Effects on Polyglutamine Conformation and Aggregation

Ashwani Kumar Thakur, Veronique M. Chellgren, Geetha Thiagarajan et al. · Journal of Molecular Biology · 2005 · 266 citations

Protein Folding, Macromolecular System, Biochemistry +1

Mutational analysis of the structural organization of polyglutamine aggregates

Ashwani Kumar Thakur, Ronald Wetzel · Proceedings of the National Academy of Sciences · 2002 · 212 citations · Full text

Slow Amyloid Nucleation via α-Helix-Rich Oligomeric Intermediates in Short Polyglutamine-Containing Huntingtin Fragments

Murali Jayaraman, Ravindra Kodali, Bankanidhi Sahoo et al. · Journal of Molecular Biology · 2011 · 212 citations · Full text

Protein Chemistry, Protein Assembly, Biochemistry +6

Polyglutamine aggregation nucleation: Thermodynamics of a highly unfavorable protein folding reaction

Ashwani Kumar Thakur, Ronald Wetzel · Proceedings of the National Academy of Sciences · 2005 · 168 citations · Full text