Neil Bence

Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

Neil Bence, Roopal M. Sampat, Ron R. Kopito · Science · 2001 · 2.2K citations

Mitophagy, Proteasome, Molecular Biology +19

Global Impairment of the Ubiquitin-Proteasome System by Nuclear or Cytoplasmic Protein Aggregates Precedes Inclusion Body Formation

Eric J. Bennett, Neil Bence, Jayakumar Rajadas et al. · Molecular Cell · 2005 · 503 citations · Full text

Protein Function, Protein Folding, Global Impairment +10

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri et al. · Nature Medicine · 2018 · 414 citations

Medicine, Anti-cancer Agent, Small-molecule Inhibitor +8

Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, α-synuclein, and the ubiquitin–proteasome system

Ranjita Betarbet, Rosa Canet-Aviles, Todd Sherer et al. · Neurobiology of Disease · 2006 · 340 citations · Full text

Neurodegenerative Diseases, Neurobiology Of Disease, Ubiquitin–proteasome System +12

A Rhodopsin Mutant Linked to Autosomal Dominant Retinitis Pigmentosa Is Prone to Aggregate and Interacts with the Ubiquitin Proteasome System

Michelle Illing, Rahul S. Rajan, Neil Bence et al. · Journal of Biological Chemistry · 2002 · 313 citations · Full text