Concepedia

Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage

Stéphanie Passot, Fernanda Fonseca, Dominique Rolland, Michèle Marin

European Journal of Pharmaceutics and Biopharmaceutics · 2005 · 64 citations · 47 references

DOI

Concepts

References

47

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

Steven J. Prestrelski, Nicole I. Tedeschi, Tsutomu Arakawa et al. · Biophysical Journal · 1993 · 717 citations · Full text

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The mechanism of cryoprotection of proteins by solutes

John F. Carpenter, John H. Crowe · Cryobiology · 1988 · 555 citations

, , +7

Surface-Induced Denaturation of Proteins during Freezing and its Inhibition by Surfactants

Byeong S. Chang, Brent S. Kendrick, John F. Carpenter · Journal of Pharmaceutical Sciences · 1996 · 472 citations

, , +11

Separation of Freezing- and Drying-Induced Denaturation of Lyophilized Proteins Using Stress-Specific Stabilization

John F. Carpenter, Steven J. Prestrelski, Tsutomu Arakawa · Archives of Biochemistry and Biophysics · 1993 · 330 citations

, , +14

The collapse temperature in freeze drying: Dependence on measurement methodology and rate of water removal from the glassy phase

Michael J. Pikal, Saroj Shah · International Journal of Pharmaceutics · 1990 · 305 citations

, , +13