Exploitation of structural and regulatory diversity in glutamate racemases

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 834 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

A Specific Mechanism of Nonspecific Inhibition

Susan L. McGovern, Brian T. Helfand, Brian Y. Feng et al. · Journal of Medicinal Chemistry · 2003 · 605 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 530 citations

Life Sciences, Biochemistry, Molecular Biology +14

Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

James A. Seidler, Susan L. McGovern, Thompson N. Doman et al. · Journal of Medicinal Chemistry · 2003 · 480 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of an allosteric site in the caspases

Jeanne A. Hardy, Joni W. Lam, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 2004 · 241 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17