R.H.A. Folmer

Structure of the PPARα and -γ Ligand Binding Domain in Complex with AZ 242; Ligand Selectivity and Agonist Activation in the PPAR Family

Philippe Cronet, Jens Petersen, R.H.A. Folmer et al. · Structure · 2001 · 323 citations · Full text

Molecular Docking, Molecular Pharmacology, Signal Transduction +12

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 210 citations · Full text

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

Stefan Geschwindner, Lise‐Lotte Olsson, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 148 citations · Full text

Medicinal Chemistry, Drug Target, Fragment-based Lead Generation +15

Exploitation of structural and regulatory diversity in glutamate racemases

T. Lundqvist, Stewart L. Fisher, Günther Kern et al. · Nature · 2007 · 138 citations · Full text

Glutamate Racemases, Natural Sciences, Genetics +6

Floating stereospecific assignment revisited: Application to an 18 kDa protein and comparison with J-coupling data

R.H.A. Folmer, Cornelis W. Hilbers, Ruud N.H. Konings et al. · Journal of Biomolecular NMR · 1997 · 110 citations