Concepedia

ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar, Brandy Wilkinson, Paige E. Cramer, Noam Zelcer, Karen M. Mann, Bruce T. Lamb, Timothy M. Willson, Jon L. Collins,

Neuron · 2008 · 867 citations · 58 references

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58

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

, , +17

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

, , +15

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

Takeshi Kawarabayashi, Linda H. Younkin, Takaomi C. Saido et al. · Journal of Neuroscience · 2001 · 1.1K citations · Full text

, , +17

Metabolic Regulation of Brain Aβ by Neprilysin

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Science · 2001 · 954 citations

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Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Nature Medicine · 2000 · 862 citations

, , +13