ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar, +14

Neuron

Alzheimer's DiseaseBiochemistryMedicineNatural SciencesCell Death +8

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

Noam Zelcer, Cynthia Hong, Rima Boyadjian, +1

Science

LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

Steven J. Bensinger, Michelle N. Bradley, Sean B. Joseph, +8

Cell

InflammationSignal TransductionMolecular PhysiologyOxysterolMedicine +7

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

Noelia A-González, Steven J. Bensinger, Cynthia Hong, +14

Immunity

Nuclear Receptor LxrImmune ToleranceAutoimmune DiseaseImmunologyCell Death +8

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

Glen Reid, Peter R. Wielinga, Noam Zelcer, +5

Proceedings of the National Academy of Sciences

Characterization of the Transport of Nucleoside Analog Drugs by the Human Multidrug Resistance Proteins MRP4 and MRP5

Glen Reid, Peter R. Wielinga, Noam Zelcer, +5

Molecular Pharmacology

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

Noam Zelcer, Négar Khanlou, Ryan Clare, +5

Proceedings of the National Academy of Sciences

ImmunologyNeurochemical BiomarkersNeuroinflammationInflammationAlzheimer's Disease +22

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)

Noam Zelcer, Glen Reid, Peter R. Wielinga, +4

Biochemical Journal

Lipid PeroxidationMolecular BiologyBile Acid ConjugatesHuman Multidrug-resistance ProteinOxidative Stress +15

Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)

Noam Zelcer, Tohru SAEKI, Glen Reid, +2

Journal of Biological Chemistry

Drug TargetLipid PeroxidationCellular PharmacologyEtoposide ResistanceOxidative Stress +15

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

Mahfoud Assem, Erin G. Schuetz, Markos Leggas, +10

Journal of Biological Chemistry

Mrp4 CapabilityHepatic Mrp4Constitutive Androstane ReceptorExperimental PharmacologyOxidative Stress +20