LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

Noam Zelcer, Cynthia Hong, Rima Boyadjian, +1

Science

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

Noelia A-González, Steven J. Bensinger, Cynthia Hong, +14

Immunity

Nuclear Receptor LxrImmune ToleranceAutoimmune DiseaseImmunologyCell Death +8

An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway

Deliang Guo, Felicia Reinitz, Mary Youssef, +27

Cancer Discovery

Chemoprevention StrategyCell DeathGbm Cell LinesCancer BiologyGlioma +14

Self-Assembled Tetrahedral Hosts as Supramolecular Catalysts

Cynthia Hong, Robert G. Bergman, Kenneth N. Raymond, +1

Accounts of Chemical Research

Molecular RecognitionSupramolecular AssemblyEngineeringMacromolecular EngineeringSelf-assembled Tetrahedral Hosts +13

LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition

Xin Rong, Carolyn J. Albert, Cynthia Hong, +10

Cell Metabolism

InflammationMolecular PhysiologySignal TransductionPhysiologyImmunology +8

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

Jaspreet Sandhu, Shiqian Li, Louise Fairall, +23

Cell

Signal TransductionBiochemistryMedicineMembrane TransportPhysiology +11

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

Ayaka Ito, Cynthia Hong, Xin Rong, +6

eLife

Inflammatory Lung DiseaseInnate Immune SystemImmune RegulationImmunologyInnate Immunity +22

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Tamer Sallam, Marius Jones, Brandon J. Thomas, +20

Nature Medicine

Transcriptional RegulationEngineeringMedicineRna BiologyLong Noncoding Rna +8

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis

Tamer Sallam, Marius C. Jones, Thomas Gilliland, +11

Nature

Cholesterol MetabolismBiochemistryNatural SciencesRna BiologyMolecular Biology +4

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

Prashant Rajbhandari, Brandon J. Thomas, An-Chieh Feng, +15

Cell

ObesityChromatinEnergy HomeostasisEnergy MetabolismLimit Thermogenesis +10