Takaomi C. Saido

Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang et al. · Neuron · 2007 · 2.2K citations · Full text

Alzheimer's Disease, Synaptic Signaling, Medicine +7

Single App knock-in mouse models of Alzheimer's disease

Takashi Saito, Yukio Matsuba, Naomi Mihira et al. · Nature Neuroscience · 2014 · 1.3K citations

Alzheimer's Disease, Molecular Neuroscience, Degenerative Pathology +5

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

Takeshi Kawarabayashi, Linda H. Younkin, Takaomi C. Saido et al. · Journal of Neuroscience · 2001 · 1.1K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Aging +15

Metabolic Regulation of Brain Aβ by Neprilysin

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Science · 2001 · 944 citations

Aging, Neurochemical Biomarkers, Amyloid Beta Peptide +19

The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques

Carlo Sala Frigerio, Leen Wolfs, Nicola Fattorelli et al. · Cell Reports · 2019 · 900 citations · Full text