Bruce T. Lamb

ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar et al. · Neuron · 2008 · 854 citations · Full text

Alzheimer's Disease, Biochemistry, Medicine +10

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

Taylor R. Jay, Crystal M. Miller, Paul J. Cheng et al. · The Journal of Experimental Medicine · 2015 · 674 citations · Full text

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

Kiran Bhaskar, Megan E. Konerth, Olga N. Kokiko‐Cochran et al. · Neuron · 2010 · 640 citations · Full text

Tau Pathology, Medicine, Autophagy +7

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

Nicole Maphis, Guixiang Xu, Olga N. Kokiko‐Cochran et al. · Brain · 2015 · 588 citations · Full text

Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration

Ahmad Salehi, Jean‐Dominique Delcroix, Pavel V. Belichenko et al. · Neuron · 2006 · 541 citations · Full text

Down Syndrome, Neurodegenerative Diseases, Molecular Neuroscience +11