Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability

Molecular basis of agonism and antagonism in the oestrogen receptor

A.M. Brzozowski, A.C.W. Pike, Zbigniew Dauter et al. · Nature · 1997 · 3.3K citations

Oestrogen Receptor, Molecular Pharmacology, Signal Transduction +12

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

A.C.W. Pike · The EMBO Journal · 1999 · 968 citations · Full text

Signal Transduction, Biochemistry, Full Antagonist +10

Bioavailability of Pure Isoflavones in Healthy Humans and Analysis of Commercial Soy Isoflavone Supplements

Kenneth D.R. Setchell, Nadine M. Brown, Pankaj B. Desai et al. · Journal of Nutrition · 2001 · 962 citations · Full text

Nutrition, Pure Isoflavones, Nutrient Bioavailability +3

Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers

PC Hollman, JH de Vries, SD van Leeuwen et al. · American Journal of Clinical Nutrition · 1995 · 950 citations · Full text

Nutrition, Healthy Ileostomy Volunteers, Gastrointestinal Pharmacology +5

Soy Isoflavone Aglycones Are Absorbed Faster and in Higher Amounts than Their Glucosides in Humans

Toru Izumi, Sachiko Osawa, Akio Obata et al. · Journal of Nutrition · 2000 · 948 citations · Full text

Food Chemistry, Food Bioactive Compound, Biochemistry +7