Concepedia

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Guoliang Xu, Timothy H. Bestor, Déborah Bourc’his, Chih-Lin Hsieh, Niels Tommerup, Merete Bugge, Maj Hultén, Xiaoyan Qu, James J. Russo, E. Viégas-Pèquignot

Nature · 1999 · 1.2K citations · 25 references

DOI

Concepts

References

25

DNA Modification Mechanisms and Gene Activity During Development

R. Holliday, J. E. Pugh · Science · 1975 · 1.9K citations

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DNA hypomethylation leads to elevated mutation rates

Richard Z. Chen, Ulf Pettersson, Caroline Beard et al. · Nature · 1998 · 954 citations

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Hhal methyltransferase flips its target base out of the DNA helix

Saulius Klimašauskas, Sanjay Kumar, Richard J. Roberts et al. · Cell · 1994 · 945 citations

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

Keith D. Robertson, É. Uzvölgyi, Gangning Liang et al. · Nucleic Acids Research · 1999 · 841 citations · Full text

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Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

Karen E. Brown, Simon S. Guest, Stephen T. Smale et al. · Cell · 1997 · 798 citations · Full text

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