Richard Z. Chen

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Richard Z. Chen, Schahram Akbarian, Matthew Tudor et al. · Nature Genetics · 2001 · 1.3K citations

Synaptic Plasticity, Molecular Neuroscience, Developmental Biology +13

DNA hypomethylation leads to elevated mutation rates

Richard Z. Chen, Ulf Pettersson, Caroline Beard et al. · Nature · 1998 · 950 citations

Genome Instability, Somatic Variant, Genetic Disorder +7

DNA Hypomethylation Perturbs the Function and Survival of CNS Neurons in Postnatal Animals

Guoping Fan, Caroline Beard, Richard Z. Chen et al. · Journal of Neuroscience · 2001 · 361 citations · Full text

Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain

Matthew Tudor, Schahram Akbarian, Richard Z. Chen et al. · Proceedings of the National Academy of Sciences · 2002 · 341 citations · Full text

Transcriptional Profiling, Genetics, Genomic Mechanism +18

Expression Pattern of the Rett Syndrome Gene MeCP2 in Primate Prefrontal Cortex

Schahram Akbarian, Richard Z. Chen, Joost Gribnau et al. · Neurobiology of Disease · 2001 · 117 citations · Full text

Molecular Neuroscience, Developmental Biology, Genetic Disorder +10