Concepedia

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

Judith S. Sebolt–Leopold, David T. Dudley, Román Herrera, Keri Van Becelaere, Amy M. Wiland, Richard Gowan, Haile Tecle, Stephen D. Barrett, Alexander J. Bridges, Sally Przybranowski,

Nature Medicine · 1999 · 969 citations · 34 references

DOI

Concepts

References

34

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen et al. · Journal of Biological Chemistry · 1995 · 3.4K citations · Full text

, , +13

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

, , +15

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

Sally A. Cowley · Cell · 1994 · 2K citations

, , +8

Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase

Sam J. Mansour, Wayne T. Matten, April S. Hermann et al. · Science · 1994 · 1.4K citations

, , +17

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

Richard Marais, Judy Wynne, Richard Treisman · Cell · 1993 · 1.3K citations

, , +8