Sally Przybranowski

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

Judith S. Sebolt–Leopold, David T. Dudley, Román Herrera et al. · Nature Medicine · 1999 · 965 citations

Colon Tumors, Medicine, Receptor Tyrosine Kinase +9

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Bing Zhou, Jiantao Hu, Fuming Xu et al. · Journal of Medicinal Chemistry · 2017 · 351 citations · Full text

Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression

Yangbing Li, Jiuling Yang, Angelo Aguilar et al. · Journal of Medicinal Chemistry · 2018 · 291 citations · Full text

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

Stephen D. Barrett, Alexander J. Bridges, David T. Dudley et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 280 citations

Medicinal Chemistry, Drug Target, Biochemistry +10

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Chong Qin, Yang Hu, Bing Zhou et al. · Journal of Medicinal Chemistry · 2018 · 258 citations · Full text

Molecular Biology, Bet Proteins, Bet Inhibitors +22